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Table 1 Demographic and clinical characteristics

From: Primary antiphospholipid syndrome in pediatrics: beyond thrombosis. Report of 32 cases and review of the evidence

 

All patients n = 32 (%)

Thrombosis n = 9 (%)

Non-thrombotic n = 23 (%)

P value

 Sex (female/male)

21/11

4/5

17/6

0.11

 Age (years)

11.7 (1–15)

12.2 (1–15)

11.5 (6–15)

0.93

 Evolution time (weeks)

16 (1–108)

7.5 (1–28)

19 (1–108)

0.21

 Hematologic

29 (90%)

7 (78%)

22 (96%)

 

 Thrombocytopenia

22 (67%)

7 (78%)

15 (65%)

0.49

 AIHA

13 (41%)

2 (22%)

11 (48%)

0.18

 LAHP

2 (6%)

0

2 (9%)

0.36

 Dermatologic

23 (72%)

7 (78%)

16 (70%)

 

 Livedo reticularis

20 (63%)

7 (78%)

13 (57%)

0.26

 Raynaud's phenomenon

8 (25%)

2 (22%)

6 (26%)

0.82

 Skin ulcers

2 (6%)

0

2 (9%)

0.36

 Neurologic

5 (16%)

1 (11%)

4 (17%)

 

 Migraine

3 (9%)

1 (11%)

2 (9%)

0.83

 Cognitive impairment

3 (9%)

1 (11%)

2 (9%)

0.83

 Epilepsy

1 (3%)

1 (11%)

0

0.10

 Chorea

1 (3%)

0

1 (4%)

0.52

 Renal

4 (13%)

3 (33%)

1 (4%)

 

 Nephrotic síndrome

1 (3%)

1 (11%)

0

0.10

 Nephritic syndrome

3 (9%)

2 (22%)

1 (4%)

0.11

Clinical profile

 T

1 (3%)

1 (11%)

0

 

 H

6 (19%)

0

6 (26%)

 

 R

1 (3%)

1 (11%)

0

 

 C

1 (3%)

0

1 (4%)

 

 H + C

16 (50%)

5 (55%)

11 (48%)

 

 H + N

1 (3%)

0

1 (4%)

 

 H + C + R

2 (6%)

1 (11%)

1 (4%)

 

 H + C + N

3 (9%)

0

3 (13%)

 

 H + C + N + R

1 (3%)

1 (11%)

0

 
  1. LAHP Lupus anticoagulant with hypoprothrombinemia syndrome, AIHA Autoimmune hemolytic anemia, T Thrombosis, H Hematologic, R Renal, C Cutaneous, N Neurologic