Table 2 Increased autoantibodies depending on gender and age at autoantibody testing
autoantibodies | total (n = 499) | male (n = 166) | female (n = 333) | p-value | 3–10 years (n = 228) | 11–22 years (n = 270) | p-value | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
anti-TG | 15 | 3.0% | 4 | 2.4% | 11 | 3.3% | 0.78 | 4 | 1.7% | 11 | 4.3% | 0.12 |
anti-TPO | 20 | 4.0% | 7 | 4.2% | 13 | 3.9% | 1 | 5 | 2.1% | 15 | 5.9% | 0.04 |
anti-tTG IgA | 2 | 0.4% | 0 | – | 2 | 0.6% | 1 | 1 | 0.4% | 1 | 0.4% | 1 |
anti-tTG IgG | 2 | 0.4% | 0 | – | 2 | 0.6% | 1 | 2 | 0.8% | 0 | – | 0.23 |
CTD-Screen | 36 | 7.2% | 15 | 9.0% | 21 | 6.3% | 0.28 | 25 | 10.5% | 11 | 4.3% | 0.01 |
anti-dsDNA | 7 | 1.4% | 0 | – | 7 | 2.1% | 0.1 | 5 | 2.1% | 2 | 0.8% | 0.27 |
anti-SS-A/Ro | 1 | 0.2% | 1 | 0.6% | 0 | – | 0.33 | 0 | – | 1 | 0.4% | 1 |
anti-SS-B/La | 1 | 0.2% | 1 | 0.6% | 0 | – | 0.33 | 0 | – | 1 | 0.4% | 1 |
anti-Sm | 0 | – | 0 | – | 0 | – | 1 | 0 | – | 0 | – | 1 |
anti-U1RNP | 0 | – | 0 | – | 0 | – | 1 | 0 | – | 0 | – | 1 |
anti-CENP-B | 2 | 0.4% | 2 | 0.1% | 0 | – | 0.11 | 2 | 0.8% | 0 | – | 0.23 |
anti-Jo1 | 0 | – | 0 | – | 0 | – | 1 | 0 | – | 0 | – | 1 |
anti-Scl70 | 0 | – | 0 | – | 0 | – | 1 | 0 | – | 0 | – | 1 |
≥ 1 autoantibody | 63 | 12.6% | 23 | 13.9% | 40 | 12.0% | 0.67 | 33 | 13.8% | 30 | 11.8% | 0.5 |
≥ 2 autoantibodies | 10 | 2% | 3 | 1.8% | 7 | 2.1% | 1 | 3 | 1.3% | 7 | 2.7% | 0.34 |
≥ 3 autoantibodies | 2 | 0.4% | 0 | – | 2 | 0.6% | 1 | 1 | 0.4% | 2 | 0.8% | 1 |