| Baseline | 6 months | 18 months | |||
---|---|---|---|---|---|---|
All patients | Patients without prior CAN therapy | All patients | Patients without prior CAN | All patients | Patients without prior CAN | All patients | Patients without prior CAN |
Number of patients, N | 54 | 11 | 35 | 7 | 16 | 3 |
Number (%*) of patients in disease remission (physician assessment) | 18 Â Â (48.6) | 1 Â Â Â Â Â Â Â Â (20.0) | 19 Â Â Â Â Â Â Â Â Â (73.1) | 3 Â Â Â Â Â Â Â Â Â (75.0) | 8 Â Â Â Â Â Â Â (61.5) | 1 Â Â Â Â Â Â Â (100.0) |
Patient assessment of current disease activity; 0–10, median (min; max) | 3.0          (0; 10) | 7.0          (0; 10) | 2.5                (0; 7) | 2.0             (0; 5) | 2.0              (0; 6) | 0.5              (0; 1) |
Patient assessment of current fatigue; 0–10, median (min; max) | 5.0         (0; 10) | 5.0          (0; 9) | 3.5                   (0; 10) | 3.0            (1; 6) | 3.0              (0; 7) | 0.5              (0; 1) |
Number (%*) of patients without impairment of social life by the disease | 19 Â Â Â Â Â (46.3) | 3Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â (37.5) | 18Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â (66.7) | 3Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â (75.0) | 5Â Â Â Â Â Â Â Â Â Â Â Â Â Â (55.6) | 2Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â (66.7) |
CRP/SAA, median (mg/dl) | 0.2/0.7 | 1.1/6.8 | 0.2/0.8 | 0.1/0.4 | 0.1/0.6 | 0.5/0.7 |