Table 1 Characteristics of patients with chronic nonbacterial osteomyelitis
Characteristics | Our patients |
|---|---|
Demographics | |
Age at disease onset, years, median (range) | 9.2 (3.66–13.08) |
Female, n (%) | 10 (55.6%) |
Delay in diagnosis, months, median (range) | 10.9 (1–72) |
Follow-up, months, median (range) | 16 (3–54) |
Clinical features | |
Distribution of involvement | |
Skull, n (%) | 0 |
Nasal bone, n (%) | 0 |
Cheekbone, n (%) | 0 |
Mandible, n (%) | 1 (5.6%) |
Clavicle, n (%) | 2 (11.1%) |
Sternum, n (%) | 1 (5.6%) |
Ribs, n (%) | 1 (5.6%) |
Humerus, n (%) | 4 (22.2%) |
Radius and ulna, n (%) | 6 (33.3%) |
phalanges,n(%) | 2 (11.1%) |
Spine, n (%) | 3 (16.7%) |
Pelvis, n (%) | 3 (16.7%) |
Femur, n (%) | 14 (77.8%) |
tibiofibula, n (%) | 16 (88.9%) |
calcaneus,n(%) | 4 (22.2%) |
Initial symptoms, n (%) | |
Bone pain | 18 (100%) |
Limp | 5 (27.8%) |
Swelling | 4 (22.2%) |
Fever | 8 (44.4%) |
Comorbidities | |
arthritis, n (%) | 8 (44.4%) |
Uveitis, n (%) | 0 |
gastrointestinal symptoms | 1 (5.6%) |
Palmoplantar pustulosis | 0 |
psoriasis | 0 |
acne | 1 (5.6%) |
NBO score, median (range) | 39 (30–53) |
CNO Family history | 0 |
HLA-B27 positivity, % | 0 |
ANA positivity, % | 0 |
ESR at initial visit (mm/h) | 57.5 ± 42.2 |
ESR elevated,% | 12 (66.7%) |
CRP at initial visit (mg/L) | 48.8 ± 48.8 |
CRP elevated,% | 11 (61.1%) |