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Table 4 Clinical remission in JIA patients treated with DMARD according to treatment group. Prospective study results

From: Clinical remission and subsequent relapse in patients with juvenile idiopathic arthritis: predictive factors according to therapeutic approach

 

SDMARD alone

n = 33 (43%)

SDMARD combined

n = 6 (8%)

SDMARD BDMARD combined

n = 23 (30%)

BDMARD alone

n = 14 (18%)

Clinical remission

n = 76

p

Female sex a, n (%)

24 (73)

4 (67)

8 (35)

9 (64)

45 (59)

0.037

Persistent oligoarticular a, n (%)

19 (91)

6 (100)

4 (57)

2 (50)

31 (82)

0.048

ANA positivity a, n (%)

26 (79)

6 (100)

12 (52)

6 (43)

50 (66)

0.013

HLA B27 absence a, n (%)

31 (94)

0

12 (52)

8 (57)

57 (75)

0.005

Uveitis absence a, n (%)

27 (82)

2 (33)

21 (91)

13 (93)

63 (83)

0.006

Biologic DMARD a, n (%)

 Etanercept

0

0

5 (36)

10 (71)

15 (54)

0.040

DMARD dose tapering a, n (%)

29 (88)

3 (50)

14 (61)

11 (79)

57 (75)

0.050

  1. SDMARD Synthetic disease modifying drug, BDMARD Biologic disease modifying drug, JIA Juvenile idiopathic arthritis, n Number; ANA Antinuclear antibodies, HLA B27 Human leukocyte antigen, AE Adverse event; IQR Interquartile range, CR Clinical remission
  2. ap < 0,05 Statistically significant differences using the χ2 or Mann Whitney U tests