Table 1 Intrauterine manifestation of CINCA/NOMID patients in previous reports
Intrauterine manifestation | Reference | The number of cases | Mutation | Commentary |
|---|---|---|---|---|
Abnormal amount of amniotic fluid | Prieur AM, et al. (1987) [7] | 2 | N.D. | Polyhydramnios |
Caroli F, et al. (2006) [15] | 1 | M406I | Oligohydramnios | |
Paccaud Y, et al. (2014) [14] | 1 | E567K | Polyhydramnios | |
Our case | 1 | F566L | Polyhydramnios | |
Histological findings of placenta and umbilical cord | Prieur AM, et al. (1987) [7] | 1 | N.D. | Placenta with thrombosis and calcification Small villi and umbilical cord with polymorphonuclear infiltration |
Paccaud Y, et al. (2014) [14] | 1 | E567K | Umbilical cord infection | |
Madison E, et al. (2019) [16] | 1 | N.D. | Necrotizing funisitis | |
Our case | 1 | F566L | Neutrophilic and lymphocytic villitis Necrotizing umbilical arteritis |