Table 2 Patient characteristics in 31 children with idiopathic inflammatory myositisa
White (n = 8) | Black/Hispanic (n = 23) | p-value | |
|---|---|---|---|
Age at diagnosis (years) | 8.5 [3,11] | 4 [3,9] | 0.31 |
Female sex | 8 (100%) | 17 (73.9%) | 0.30 |
Diagnosis | |||
JDM | 8 (100%) | 20 (87%) | 0.55 |
Overlap/JPM | 0 | 3 (13%) | |
Disease duration (months) | 48 [18,102] | 27 [15,73] | 0.22 |
Weakness | |||
None/mild | 6 (71.4%) | 14 (70%) | > 0.99 |
Moderate/severe | 2 (28.6%) | 5 (30%) | |
Skin rash | |||
None | 0 | 5 (25%) | 0.48 |
Typical | 6 (85.7%) | 11 (55%) | |
Atypical | 1 (14.3%) | 4 (20%) | |
MSA/MAA | |||
Antibody negative | 2 (25%) | 0 | 0.04 |
Anti-MDA5 | 0 | 8 (34.8%) | |
Anti-p155/140 | 3 (37.5%) | 4 (17.4%) | |
Anti-MJ | 3 (37.5%) | 3 (13%) | |
Anti-Mi2 | 0 | 1 (4.4%) | |
Anti-synthetase (PL-12) | 0 | 1 (4.4%) | |
Anti-Ro | 0 | 4 (17.4%) | |
Anti-RNP | 0 | 1 (4.4%) | |
Anti-PM-Scl | 0 | 1 (4.4%) | |
Disease features | |||
Ulceration | 0 | 7 (33.3%) | 0.14 |
Calcinosis | 2 (28.6%) | 7 (33.3%) | > 0.99 |
Lipodystrophy | 0 | 3 (14.3%) | 0.55 |
Gastrointestinal | 1 (14.3%) | 8 (38.1%) | 0.37 |
Cardiac | 0 | 3 (13.6%) | > 0.99 |
Pulmonary | 0 | 11 (50%) | 0.03 |
Disease Course | |||
Hospitalizationsb | 0 | 7 (38.1%) | 0.08 |
Death | 0 | 1 (4%) | > 0.99 |