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Fig. 4 | Pediatric Rheumatology

Fig. 4

From: The culture microenvironment of juvenile idiopathic arthritis synovial fibroblasts is favorable for endochondral bone formation through BMP4 and repressed by chondrocytes

Fig. 4

Using ELISA, protein expression was determined for BMP antagonists. CFLS-Ch had significant increases in total protein expressio of BMP antagonists at 24 h (NOG (p = 0.002), CHRD (p = 0.002), gremlin (GREM) (p = 0.001), and follistatin (FST) (p = 0.002)) when compared with CFLS (a). Conditioned media from Ch influence JFLS to increase total protein amounts of BMP antagonists NOG (p = 0.001), CHRD (p = 0.000), GREM (p = 0.000), and FST (p = 0.000) (b)

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Pediatric Rheumatology

ISSN: 1546-0096