Fig. 5

Association of baseline serum biomarkers and inflammatory parameters with disease activity outcome at 12 months. a Inflammatory parameters and serum biomarkers of treatment naïve patients at study inclusion (n = 54) were associated with clinical disease activity according to cJADAS-10 at 12-month follow-up (inactive disease: ≤1). b, c Indicated parameters assessed at baseline were (almost) significantly different when associated with clinical outcome at 12-month follow-up. d In the same sub-cohort of treatment naïve patients (n = 54), baseline inflammatory parameters and serum biomarkers were associated with clinical disease activity according to active joint count (AJC) at 12-month follow-up. e, f Indicated parameters assessed at baseline revealed significant differences when associating with clinical outcome at 12-month follow-up. Data are presented as violin plots with individual values or ROC (only significantly different parameters) and were analyzed by Mann-Whitney U test. * = p < 0.05, ** = p < 0.01