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Table 1 Patient demographics and clinical data

From: Factors associated with reduced infliximab exposure in the treatment of pediatric autoimmune disorders: a cross-sectional prospective convenience sampling study

Patient Characteristics

Study Population

IBD

JIA

Uveitis

Patients, n

97

73

16

8

Gender, female, n (%)

43 (44)

29 (40)

10 (63)

4 (50)

Age, yr, median [range]

16 [5,21]

16 [5,21]

13 [7,20]

16 [6,21]

Diagnosis, n (%)

 IBD

73 (75)

   

 JIA

16 (17)

   

 Uveitis

8 (8)

   

IFX Dosing, median [IQR]

 Dose, mg/kg

8.4 [6.5,9.8]

7.7 [6.2,9.4]

9.7 [8.5,10.7]*

10.5 [7.5,12.0]#

 Interval, weeks

6 [4,7]

6 [4,8]

4 [4,5]*

4 [4,6]#

Immunomodulator, n (%)

 MTX

37 (38)

19 (26)

12 (75)*

6 (75)#

 AZA

3 (3)

3 (4)

0 (0)

0 (0)

Inflammatory Markers, median [IQR]

 ESR, mm/hr

9 [6,17.5]

9 [7,17]

7 [6,17]

13 [7,22]

 CRP, mg/dL

0.5 [0.5,0.8]

0.5 [0.5,0.8]

0.5 [0.5,0.6]

0.7 [0.6,0.8]

 Albumin, g/dL

4.3 [4.0,4.5]

4.3 [4.0,4.5]

4.3 [4.2,4.6]

4.3 [4.0,4.6]

  1. *, IBD vs JIA, significant at p < 0.05
  2. #, IBD vs Uveitis, significant at p < 0.05