Table 4 Bone remodeling factors in JDM patients and controls
|  | Patients (n = 55–58) | Controls (n = 55–58) | p-values |
|---|---|---|---|
CTX, ug/l | 0.51 (0.34–0.97) | 0.46 (0.30–0.96) | 0.34 |
P1NP, ug/l | 73.0 (46.8–318.0) | 75.0 (52.8–352.0) | 0.63 |
25-OH-VitD, nmol/l | 54.0 (37.0–65.0) | 65.0 (45.0–83.0) | 0.001 |
Low 25(OH)VitD (<  37 nmol/l), n | 13 (22.4) | 4 (6.9) | 0.08 |
Insufficient 25(OH)VitD (<20nmo/l), n | 3 (5.5) | 0 (0) | 0.02 |
Calsium, nmol/l | 2.29 (2.24–2.33) | 2.33 (2.29–2.39) | 0.001 |
iCalsium, nmol/l | 1.25 (0.04) | 1.25 (0.03) | 0.83 |
Albumin, g/l | 44.5 (2.3) | 45.9 (2.3) | 0.002 |
Alkaline phosphatase, U/l | 71.0 (56.0–147.3) | 72.00 (55.0–150.8) | 0.97 |
Phosphate, nmol/l | 1.23 (0.25) | 1.13 (0.21) | 0.005 |
PTH, pmol/l | 3.52 (1.19) | 3.53 (1.27) | 0.95 |
E-SR, mm/h | 5.0 (3.0–9.0) | 4.0 (3.0–8.0) | 0.06 |
hsCRP, mg/l | 0.98 (0.28–2.6) | 0.59 (0.23–1.27) | 0.12 |
IP-10, pg/ml | 1009 (911–1581) | 969 (751–1187) | 0.04 |
Age < 20 y | (n = 25–28) | (n = 25–28) |  |
CTX, ug/l | 0.94 (0.55–1.39) | 0.97 (0.49)1.22 | 0.73 |
P1NP, ug/l | 326.0 (95.0–560.78) | 397.0 (95.0–608.7) | 0.77 |
25-OH-VitD, nmol/l | 55.4 (19.0) | 66.2 (24.4) | 0.11 |
Low 25(OH)VitD (< 37 nmol/l), n | 6 (21.4) | 2 (7.1) | 0.31 |
Insufficient 25-OH-VitD (<20 nmol/l), n | 1 (3.7) | 0 (0) | 0.13 |
Calsium, nmol/l | 2.3 (0.2) | 2.3 (0.01) | 0.18 |
iCalsium, nmol/l | 1.26 (0.03) | 1.26 (0.03) | 0.75 |
Albumin, g/l | 44.8 (2.1) | 45.8 (2.1) | 0.10 |
Alkaline phosphatase, U/l | 149.5 (74.3–226.8) | 152.5 (76.5–194.8) | 0.60 |
Phosphate, nmol/l | 1.35 (0.23) | 1.23 (0.23) | 0.005 |
PTH, pmol/l | 3.55 (1.23) | 3.32 (1.28) | 0.50 |
E-SR, mm/h | 4.50 (3.00–8.25) | 4.50 (3.00–10.50) | 0.44 |
hsCRP, mg/l | 0.40 (0.24–2.44) | 0.35 (0.19–1.27) | 0.43 |
IP-10, pg/ml | 982 (855–1479) | 889 (732–1125) | 0.14 |
Age ≥ 20 y | (n = 28–30) | (n = 28–30) |  |
CTX, ug/l | 0.40 (0.24–0.49) | 0.32 (0.23–0.41) | 0.16 |
P1NP, ug/l | 55.0 (41.8–59.0) | 59.0 (42.8–68.0) | 0.23 |
25(OH)VitD, nmol/l | 47.3 (17.2) | 65.3 (21.4) | 0.001 |
Low 25(OH)VitD (< 0.37 nmol/l), n | 7 (23.3) | 2 (6.7) | 0.15 |
Insufficient 25(OH)VitD (<20 nmol/l), n | 2 (7.1) | 0 (0) | 0.07 |
Calsium, nmol/l | 2.25 (0.11) | 2.34 (0.09) | 0.002 |
iCalsium, nmol/l | 1.24 (0.04) | 1.24 (0.03) | 0.62 |
Albumin, g/l | 44.3 (2.5) | 46.0 (2.5) | 0.004 |
Alkaline phosphatase, U/l | 61.0 (49.0–73.3) | 59.0 (50.0–70.5) | 0.66 |
Phosphate,nmol/l | 1.10 (0.22) | 1.03 (0.17) | 0.15 |
PTH, pmol/l | 3.5 (1.17) | 3.73 (1.44) | 0.48 |
E-SR, mm/h | 7.0 (3.0–8.5) | 4.0 (3.0–8.0) | 0.08 |
hsCRP, mg/l | 1.07 (0.43–3.5) | 0.63 (0.33–1.27) | 0.15 |
IP-10, pg/ml | 1066 (940–1593) | 1041 (764–1201) | 0.14 |