Table 1 SSc-related autoantibodies
SSc-related autoantibodies | Measurement methods | Present Case |
|---|---|---|
Antinuclear antibodies (ANA) | Indirect immunofluorescence | 1:160 nucleolar and homogeneous nuclear |
Anti-topoisomerase I (anti-Scl70) | Chemiluminescent enzyme immunoassay (commercially available) | negative |
Anticentromere | Enzyme-linked immunosorbent assay (commercially available) | negative |
Anti-RNA polymerase III | Enzyme-linked immunosorbent assay (commercially available) | negative |
Anti-U1RNP | Chemiluminescent enzyme immunoassay (commercially available) | negative |
Anti-Th/To | Immunoprecipitation-immunoblot assay | positive |
Anti-PM-Scl | Immunoprecipitation-immunoblot assay | positive |