From: Early combination therapy with etanercept and methotrexate in JIA patients shortens the time to reach an inactive disease state and remission: results of a double-blind placebo-controlled trial
Phase
Group
MTX
ETA + MTX
Phase 1
7 patients (21%)
(11 AEs)
4 patients (11%)
(6 AEs)
Phase 2
3 patients (15%)
(3 AEs)
5 patients (11%)
(5 AEs)
Phase 3
3 patients (33%)
9 patients (17%)
(14 AEs)