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Table 2 Laboratory parameters in pediatric IgA vasculitis patients in different onset age groups

From: Onset age is a risk factor for refractory pediatric IgA vasculitis: a retrospective cohort study

 

≤6 Y (n = 234)

6–12 Y (n = 210)

12–18 Ya (n = 40)

P value

Hb (g/dl)

12.60 (11.9–13.3) (n = 178)

13.10 (12.30–13.70) (n = 161)

13.55 (12.95–14.40) (n = 24)

<  0.001

Plt (109/L)

346.0 (284.0–427.0) (n = 178)

345.0 (300.0–406.0) (n = 161)

345.5 (260.8–389.8 (n = 24)

0.309

WBC(109/L)

10,600 (8622–12,950) (n = 180)

10,615 (8478–13,365) (n = 158)

9900 (8358–11,545) (n = 24)

0.609

Neutrophil (109/L)

6250 (4593–8177) (n = 177)

7166 (5115–10,156) (n = 151)

6171 (5229–8103) (n = 24)

0.049

Lymphocyte (109/L)

3211.5 (2460–4147.1) (n = 177)

2598.7(1879.5–3348.9) (n = 150)

2195 (1645–2872) (n = 24)

<  0.001

NLR

1.91 (1.26–2.82) (n = 177)

2.95 (1.60–4.61) (n = 150)

2.68 (1.90–4.68) (n = 24)

<  0.001

PLR

108.59 (80.38–141.61)

(n = 175)

126.89 (100.71–190.99) (n = 150)

154.00 (106.67–183.42) (n = 24)

<  0.001

IgA (mg/dL)

189.5 (137.8–259.0) (n = 168)

253.5 (217.0–340.5) (n = 154)

308.5 (231.0–395.8) (n = 30)

<  0.001

ANA≧1:80 positive

12/154

14/143

2/30

0.767

CRP≧1 mg/dL

63/151

42/120

12/19

0.059

  1. Data are presented as median (IQR)
  2. Abbreviations: Hb Hemoglobin, Plt Platelet, WBC White blood cells, PLR Platelet-to-lymphocyte ratio, NLR Neutrophil-to-lymphocyte ratio, IgA Immunoglobulin A, ANA Antinuclear antibody, CRP C-reactive protein
  3. a Patients were grouped by onset age: ≤ 6 Y (years old), 6–12 Y (> 6, ≤ 12 years old), and 12–18 Y (> 12, < 18 years old)