Table 1 Demographic and clinical manifestations in pediatric IgA vasculitis according to different onset ages
From: Onset age is a risk factor for refractory pediatric IgA vasculitis: a retrospective cohort study
|  | Total (n = 484) | ≤6 Y (n = 234) | 6–12 Y (n = 210) | 12–18 Ya (n = 40) | P value |
|---|---|---|---|---|---|
Onset age, years old | 6.10 (4.72–8.58) | 4.68 (3.83–5.27) | 7.91 (6.88–9.55) | 14.48 (12.97–15.90) |  |
Male sex | 252 (52.1%) | 122 (52.1%) | 110 (52.4%) | 20 (50.0%) | 0.962 |
Preceding infection | 304 (62.8%) | 168 (71.8%) | 118 (56.2%) | 16 (40.0%) | < 0.001 |
Manifestation | |||||
 Skin purpura | 484 (100%) | 234 (100%) | 210 (100%) | 40 (100%) | NA |
 Arthralgia/arthritis | 361 (74.6%) | 192 (82.1%) | 151 (71.9%) | 18 (45.0%) | < 0.001 |
 CNS/PNS involvement | 5 (1.0%) | 2 (0.9%) | 2 (1.0%) | 1 (2.5%) | NA |
 GI involvement | 311 (64.3%) | 156 (66.7%) | 130 (61.9%) | 25 (62.5%) | 0.562 |
 Abdominal pain | 294 (60.7%) | 147 (62.8%) | 123 (58.6%) | 24 (60.0%) | 0.654 |
 Vomiting | 100 (20.7%) | 50 (21.4%) | 44 (21.0%) | 6 (15.0%) | 0.649 |
 Diarrhea | 34 (7.0%) | 11 (4.7%) | 18 (8.6%) | 5 (12.5%) | 0.103 |
 GI bleeding | 42 (8.7%) | 23 (9.8%) | 15 (7.1%) | 4 (10.0%) | 0.576 |
 Positive stool occult blood | 111 (22.9%) | 56 (23.9%) | 44 (21.0%) | 11 (27.5%) | 0.586 |
 Renal involvement | 130 (26.9%) | 43 (18.4%) | 65 (31.0%) | 22 (55.0%) | < 0.001 |
 Microscopic hematuria | 129 (26.7%) | 43 (18.5%) | 64 (30.5%) | 22 (55.0%) | < 0.001 |
 Gross hematuria | 10 (20.7%) | 4 (1.7%) | 6 (2.9%) | 0 | NA |
 Non-nephrotic proteinuria | 24 (5.0%) | 8 (3.4%) | 13 (6.2%) | 3 (7.5%) | 0.301 |
 Nephrotic syndrome | 8 (1.7%) | 2 (0.9%) | 5 (2.4%) | 1 (2.5%) | NA |