Table 4 Estimates of factors associated with cJADAS over time in mixed-effects models in pre-intervention and Phase II implementation cohorts
Univariate * | Multivariate | |||
|---|---|---|---|---|
β (95% CI) | p-value | β (95% CI) | p-value | |
Age | 0.61 (−0.32,-0.00) | 0.05 | – | – |
Male Sex | −1.62 (− 2.77,-0.46) | < 0.01 | – | – |
Public insurance | −0.38 (− 1.50,0.74) | 0.50 | – | – |
Baseline cJADAS | 0.61 (0.52,0.69) | < 0.01 | 0.47 (0.38,0.55) | < 0.01 |
Polyarticular disease | 0.80 (−0.40,1.99) | 0.19 | – | – |
Sacroiliitis (ever) | −1.32 (− 2.57,-0.08) | 0.04 | – | – |
Incident diagnosis | 3.12 (2.00,4.20) | < 0.01 | 0.26 (−0.52,1.03) | 0.52 |
Time (in months) | −0.17 (− 0.33,− 0.01) | 0.04 | -0.01 (− 0.13, 0.10) | 0.81 |
Incident diagnosis* time interaction^ | − 0.39 (− 0.75,-0.02) | 0.04 | −0.32 (− 0.56,-0.08) | < 0.01 |
Pain VAS # | 0.94 (0.79,1.09) | < 0.01 | 0.72 (0.60,0.85) | < 0.01 |
Tender entheses count # | 0.57 (0.40,0.74) | < 0.01 | – | – |
Biologic use # | −2.02 (− 3.02,-1.01) | < 0.01 | – | – |
Pre-intervention vs Phase II cohort | 0.33 (−0.77,1.44) | 0.56 | – | – |
Pre-intervention vs Phase II cohort * time interaction^ | −0.04 (− 0.36,0.29) | 0.82 | – | – |