Fig. 5From: Is fibrodysplasia ossificans progressiva an interleukin-1 driven auto-inflammatory syndrome?Number of FOP flares per month, based on documentation held by the patient’s family, the patient’s pediatrician and the rheumatology unit. Note the marked change in the mean number of flares, just after the initiation of anti-IL-1 treatment (between the dashed blue lines), and a temporary elevation in flare frequency while canakinumab was withheldBack to article page