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Table 1 Demographic info and baseline characteristics at initial clinical visit with OMS or PR at SCH (n = 22)

From: Pediatric chronic nonbacterial osteomyelitis of the mandible: Seattle Children’s hospital 22-patient experience

Study Variable

Median (IQR) or number (frequency)

Female, n (%)

8 (36)

Age (yr)

11 (7–12)

HLA-B27 positivity, n (%) (15 available)

1 (7)

ANA positivity, n (%) (10 available)

3 (30)

ESR (mm/hr) at initial visit, (n = 20)

16 (9–35)

CRP (mg/dL) at initial visit, (n = 20)

2.3 (0.8–1.9)

Treating Service, n (%)

 Rheum and OMS

15 (68)

 OMS only

3 (14)

 Rheum only

4 (18)

 Multifocal lesions, n (%)

4 (18)

 Clavicle

1 (5)

 Lower extremity (femur, tibia/ fibula, foot)

3 (14)

 Upper extremity (radius/ ulna, humerus)

1 (5)

Pre-SCH care, n (%)

 Outside OMS

7 (32)

 Biopsies

9 (41)

 Resection

1 (5)

 Antibiotics

16 (73)

SCH surgical care, n (%)

 Biopsies (intraoral)

12 (55)

 Biopsies (extraoral)

1 (5)

 Return to OR/ additional surgery*

2 (9)

SCH medical care, n (%)

 Antibiotics

9 (41)

 NSAIDs

18 (82)

 Glucocorticoids

10 (45)

 DMARDs (MTX, sulfasalazine)

9 (41)

 Pamidronate

6 (27)

 Anti-TNF therapy

5 (23)

  1. HLA: human leucocyte antigen; ANA: antinuclear antibody; OMS: oral maxillary surgery; ESR: erythrocyte sedimentation rate; CRP: c reactive protein; NSAID: nonsteroidal anti inflammatory drug; DMARD: disease modifying anti rheumatic drug; MTX: methotrexate. TNF: tumor necrosis factor;
  2. *Return to OR/ additional surgery was for mandibular recontouring. Additional extractions/dento-alveolar procedures were excluded