Predictive value of serum procalcitonin for both initial and repeated immunoglobulin resistance in Kawasaki disease: a prospective cohort study

Table 3 The validity of PCT in predicting initial IVIG resistance for the total group and the abnormal PCT group

Initial IVIG resistance	Diagnostic test	Gold standard			Sen	Spe	PPV	NPV	Diagnostic accuracy	OR(95%CI)	P
Total group(n = 530)	PCT ≥ 1.48 ng/ml	positive	41	128	0.54	0.72	0.24	0.90	0.69	2.98 (1.82–4.90)	< 0.001*
Total group(n = 530)	PCT ≥ 1.48 ng/ml	negative	35	326	0.54	0.72	0.24	0.90	0.69	2.98 (1.82–4.90)	< 0.001*
Abnormal PCT group(n = 305)	PCT ≥ 1.81 ng/ml	positive	38	110	0.67	0.56	0.26	0.88	0.58	2.51(1.37–4.60)	0.002*
Abnormal PCT group(n = 305)	PCT ≥ 1.81 ng/ml	negative	19	138	0.67	0.56	0.26	0.88	0.58	2.51(1.37–4.60)	0.002*

CI confidence ratio, NPV negative predictive value, OR odds ratio, PCT procalcitonin, PPV positive predictive value, Sen sensitivity;
Spe specificity;
*Statistically significant (P < 0.05)

ISSN: 1546-0096