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Table 2 Clinical Characteristics, N = 167 (single injection)

From: Retrospective review of immobilization vs. immediate resumption of activity in patients with Oligoarticular juvenile idiopathic arthritis following knee injections

N(%) or Median (25th–75th)  
  All (N = 167) CHOP (N = 72) TSRH (N = 95) P-value* SMD
Joint swelling
  > 1 (vs 0) 161 (96%) 69 (96%) 92 (97%) 1.00 0.05
Joint tenderness
  > 1 (vs 0) 30 (18%) 27 (38%) 3 (3%) < 0.0001 0.94
Joint range of motion
  > 1 (vs 0) 95 (57%) 34 (47%) 61 (64%) 0.0281 0.35
 Total joints active     0.0046 0.58
 1 90 (54%) 30 (42%) 60 (63%)   
 2 58 (35%) 28 (39%) 30 (32%)   
 3 13 (8%) 8 (11%) 5 (5%)   
 4 4 (2%) 4 (6%) 0   
 5 0 0 0   
 6 2 (1%) 2 (3%) 0   
 2+ Joints Active (vs 1 only) 77 (46%) 42 (58%) 35 (37%) 0.0058 0.44
 Pain Assessment (1–10)a 1 (0–4) 0 (0–4) 2 (0–4) 0.0081 0.56
 CHAQ Scoreb 0.125 (0–0.50) 0.125 (0–0.125) 0.125 (0–0.50) 0.39 0.28
 MD Global Scorec 1(1–2) 2 (2–4) 1 (1–2) < 0.0001 1.80
 ANA status–Positive 108 (66%) 39 (55%) 69 (74%) 0.0099 0.41
 RF status– Positive 4 (3%) 2 (3%) 2 (2%) 1.00 0.05
 HLA-B27 status–Positive 14 (13%) 5 (11%) 9 (14%) 0.68 0.08
 ESRd 14 (8–23) 12 (5–28) 14 (8–21.5) 0.48 0.14
 On injection DMARDs 29 (17%) 12 (17%) 17 (18%) 0.84 0.03
 On injection biologics 7 (4%) 6 (8%) 1 (1%) 0.0432 0.35
 On NSAIDs 109 (65%) 49 (68%) 60 (63%) 0.51 0.10
 Total joints injected     0.0002 0.60
 2+ 53 (32%) 34 (47%) 19 (20%)   
 1 114 (68%) 38 (53%) 76 (80%)   
 Steroid injection – Aristopan (vs. Kenalog) 156 (94%) 66 (92%) 90 (96%) 0.33 0.12
 Knee injection dose (mg) 10 (2–20) 10 (2–20) 10 (2–20) 0.0132 0.40
 Knee injection dose (mg/kg) 0.33 (0.10–0.78) 0.43 (0.13–0.90) 0.27 (0.10–0.72) 0.26 0.19
  1. *Wilcoxon Rank-Sum tests or Chi-Squared/Fisher’s Exact Tests between CHOP and TSRH sites, alpha = 0.05
  2. aPain Assessment is missing for 42% (n = 70) of the data
  3. bCHAQ score missing for 56% (n = 94) of the data
  4. cMD Global score missing for 46% (n = 77) of the data
  5. dESR score missing for 31% (n = 52) of the data
  6. SMD: standardized mean difference. SMD > 0.25 (25%) indicates an imbalance between groups, P < 0.05 is considered statistically significant (shown in bold)