Table 3 Outcome of biological treatment in 28 flares of 13 pediatric patients
Targets | Flares n | Clinical response [flares n (%)] | Median treatment duration in months (range) | ||
|---|---|---|---|---|---|
CR | PR | NR | |||
TNF-a | 12 | 7 (58) | 1 (8) | 4 (33) | 6.5 (0.2–26) |
IL-1 | 8 | 1 (13) | 1 (13) | 6 (76) | 2.5 (0.1–36) |
IL-12/23 | 4 | 4 (100) | – | – | 13.5 (5–31) |
IL-17 | 4 | 4 (100) | – | – | 8 (2–12) |
Total | 28 | 16 (57) | 2 (7) | 10 (36) | 5.5 (0.1–36) |