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Table 3 Outcome of biological treatment in 28 flares of 13 pediatric patients

From: Scoping review of biological treatment of deficiency of interleukin-36 receptor antagonist (DITRA) in children and adolescents

Targets Flares n Clinical response [flares n (%)] Median treatment duration in months (range)
   CR PR NR  
TNF-a 12 7 (58) 1 (8) 4 (33) 6.5 (0.2–26)
IL-1 8 1 (13) 1 (13) 6 (76) 2.5 (0.1–36)
IL-12/23 4 4 (100) 13.5 (5–31)
IL-17 4 4 (100) 8 (2–12)
Total 28 16 (57) 2 (7) 10 (36) 5.5 (0.1–36)
  1. Abbr. CR-complete response, PR-partial response, NR-no response.