Table 1 Clinical criteria for the diagnosis of FMF
From: Periodic fever syndromes: beyond the single gene paradigm
Tel Hashomer clinical criteria (3) | |
 Diagnostic criteria: | One or more major signs; or Two minor signs; or One minor and five supportive criteria |
 Major criteria: | ≥3 attacks of the same type, with rectal temperature ≥ 38 °C, lasting 12–72 h, as well as:  Peritonitis  Pleuritis or pericarditis  Monoarthritis (hip, knee, ankle)  Fever alone |
 Minor criteria: | Incomplete attacks involving 1 or more of abdomen, chest, joint Exertional leg pain Favourable response to colchicine |
 Supportive criteria: | Family history of FMF Appropriate ethnic origin Age < 20 yr. at disease onset Features of attacks: severe; spontaneous remission; symptom-free intervals; transient inflammatory response with abnormal WBC, ESR, SAA, or fibrinogen; episodic proteinuria/hematuria; unproductive laparotomy; parental consanguinity |
Yalcinkaya clinical criteria for children (4) | |
 Requires ≥3 attacks with ≥2 of the following: | |
|  | Fever with axillary temperature > 38 °C lasting 6–72 h Abdominal pain lasting 6–72 h Chest pain lasting 6–72 h Oligoarthritis lasting 6–72 h Family history of FMF |