Fig. 3

Time course of JIA-ACR core set variables improvement from baseline to Week 52 of the cumulative period. The six JIA-ACR core set variables were evaluated as the median (%) improvement from baseline at indicated time points (all treated patients; N = 20). CHAQ-DI Childhood Health Assessment Questionnaire-Disability Index, CRP C-reactive protein, JIA-ACR Juvenile idiopathic arthritis-American College of Rheumatology criteria, LOM limitation of motion, PaGA Parental Global Assessment of patient overall well-being, PGA Physician Global Assessment