Increase expression of CD177 in Kawasaki disease

Table 2 The ideal genes for possessing negative correlation with CpG markers with a 5% change in M450K and a two-fold change in HTA 2.0 between KD patients and controls

Symbol	Annotated Term	RefSeq	Fold-Change (KD1 vs. HC)	p-value (KD1 vs. HC)	Fold-Change (KD1 vs. FC)	p-value (KD1 vs. FC)	Fold-Change (KD3 vs. KD1)	p-value (KD3 vs. KD1)
CD177	Glycoprotein, Neutrophil migration	NM_020406	11.263	0.001*	3.429	0.032*	−9.022	0.002*
VNN1	Glycoprotein	NM_004666	4.850	0.000*	2.508	0.000*	−5.969	0.000*
NLRC4	Apoptosis, Innate immunity	NM_001199138	4.454	0.000*	2.159	0.015*	−4.761	0.000*
S100A12	Antibiotic, Innate immunity, Neutrophil migration	NM_005621	3.899	0.001*	2.037	0.033*	−4.524	0.001*
GPR84	Glycoprotein	NM_020370	3.821	0.004*	2.266	0.041*	−4.167	0.003*
ARG1	Arginase activity, Manganese ion binding	NM_000045	3.735	0.001*	2.020	0.019*	−4.083	0.000*
CLEC4D	Glycoprotein, Innate immunity	NM_080387	3.684	0.008*	2.873	0.022*	−4.474	0.004*
HP	Glycoprotein, Immunity	NM_001126102	3.681	0.000*	2.387	0.005*	−3.993	0.000*
EMR1	G-protein coupled receptor activity	NM_001256252	3.610	0.002*	2.285	0.017*	−2.822	0.006*
CR1	Innate immunity, Glycoprotein	NM_000573	2.885	0.001*	2.333	0.004*	−2.915	0.001*
P2RY14	Glycoprotein	NM_001081455	2.851	0.005*	2.266	0.017*	−2.636	0.008*
CLC	Carbohydrate binding	NM_001828	2.754	0.018*	2.482	0.029*	−2.065	0.067
LPCAT2	Calcium ion binding	NM_017839	2.116	0.009*	2.227	0.006*	−2.070	0.010*
IL1B	Inflammatory response, Neutrophil migration	NM_000576	1.677	0.066	2.195	0.012*	−2.475	0.006*

KD1 Kawasaki disease before IVIG treatment, KD3 Kawasaki disease > 3 weeks after IVIG treatment, FC febrile control, HC healthy control
*indicate p value < 0.05

ISSN: 1546-0096