Table 1 (abstract P2073). The parameters of renal functions and acute phase reactants in patients with initial creatinine level below 1.5mg/dL (Group 1) and above 1.5mg/dL (Group 2)
From: 10th Congress of International Society of Systemic Auto-Inflammatory Diseases (ISSAID)
| Â | Before treatment | After treatment | p | Before treatment | After treatment | p | Before treatment | After treatment | p |
|---|---|---|---|---|---|---|---|---|---|
Group 1 | Anakinra(n= 19) | Canakinumab (n=10) | All anti IL-1 (n=23) | ||||||
 Creatinine (mg/dl) | 0,9 ± 0,28 | 0,9 ± 0,44 | <0,01 | 1,35 ± 1,57 | 1,78 ± 1,93 | 0,01 | 0,8 ± 0,25 | 1,3 ± 1,5 | <0,01 |
 Proteinuria (mg/day) | 2686 ± 3257 | 2328 ± 4458 | <0,01 | 6000 ± 5550 | 3730 ± 5030 | <0,01 | 2780 ± 3323 | 1365 ± 2365 | <0,01 |
 ESR(0-20 mm/h) | 43,5 ± 31,3 | 19,3 ± 26,4 | <0,01 | 51,22 ± 33,54 | 17,1 ± 31,2 | <0,01 | 44,8 ± 31,1 | 17,6 ± 31,1 | <0,01 |
Group 2 | Anakinra(n= 13) | Canakinumab (n=9) | All anti IL-1 (n=17) | ||||||
 Creatinine (mg/dl) | 3,3 ± 2,4 | 3,4 ± 2,4 | <0,01 | 3,1 ± 2,4 | 3,2 ± 2,5 | <0,01 | 3,54 ± 2,62 | 3,5 ± 2,59 | <0,01 |
 Proteinuria (mg/day) | 5482 ± 8040 | 3651 ±4635 | 0,01 | 7670 ± 7600 | 7585 ± 6830 | 0,01 | 5347 ± 7377 | 3130 ± 4764 | 0.01 |
 ESR (0-20 mm/h) | 56,8 ± 35,1 | 31,3 ± 17,8 | <0,01 | 51,22 ± 33,54 | 34,55 ± 27,19 | <0,01 | 56,8 ± 34,6 | 38,8 ± 27,6 | <0,01 |