From: 10th Congress of International Society of Systemic Auto-Inflammatory Diseases (ISSAID)
Parameter | EO-CNO (n=17) | “CNO w/o RD” (n=59) | CNO with RD (n=20) | p1 |
---|---|---|---|---|
Onset age, years | 3.0 (2.1-4.8) | 7.3 (2.8-11.7) | 10.3 (8.2-12.2) | 0.0009 |
Gender, females | 8 (47.1) | 27 (45.8) | 14 (70.0) | 0.17 |
Fever at onset | 9/16 (56.3) | 23 (39.0) | 5 (25.0) | 0.16 |
Foci number | 5.0 (1.5-6.0) | 3.0 (1.0-4.0) | 2.0 (1.0-6.0) | 0.048 |
Symptomatic arthritis | 15/16 (93.8) | 33 (55.9) | 17 (85.0) | 0.003 |
North Caucasus origin | 17 (100.0) | 0 (0.0) | 0 (0.0) | <0.00001 |
Granulematosus inflammation (tuberculosis-like) | 17 (100.0) | 0 (0.0) | 0 (0.0) | <0.00001 |
Prevalence of CNO | 1: 55,000 | 1:450,000 | 1:1,375,000 | <0.00001 |