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Table 4 HLH/MAS Evidence-Based Guideline Quality Metrics

From: Calm in the midst of cytokine storm: a collaborative approach to the diagnosis and treatment of hemophagocytic lymphohistiocytosis and macrophage activation syndrome

Quality Improvement Outcome Measures
Length of hospital stay (days)
Hospital readmission within 60 days (Y/N)
Time to HLH/MAS diagnosis (days)
Time to initiation of HLH/MAS directed therapy (days)
Fever duration (days)
Ferritin decrease by 50% of maximum during hospital stay (Y/N)
Time to decrease of ferritin by 50% of maximum (days)
Time to CRP < 1 mg/dL (days)
Need for higher level of care such as ICU/ICP (Y/N)
Mortality (Y/N)
  1. HLH hemophagocyticlymphohistiocytosis, MAS macrophage activation syndrome, ICU intensive care unit, ICP intermediate care program