Age
|
1.11
|
1.09–1.14
|
< 0.001
|
1.09
|
1.04–1.14
|
< 0.001
|
BMI
|
1.07
|
1.05–1.10
|
< 0.001
|
1.01
|
0.97–1.05
|
0.656
|
Female sex
|
1.30
|
1.11–1.52
|
0.001
|
1.00
|
0.78–1.28
|
1.000
|
Disease duration
|
0.99
|
0.99–1.00
|
0.049
| | | |
Age at disease onset
|
1.08
|
1.06–1.10
|
< 0.001
|
1.03
|
1.00–1.06
|
0.041
|
RF-positive polyarthritis
|
1.60
|
1.13–2.26
|
0.008
|
1.25
|
0.74–2.13
|
0.407
|
RF-negative polyarthritis
|
0.98
|
0.83–1.16
|
0.831
|
0.73
|
0.55–0.97
|
0.028
|
Systemic JIA
|
0.96
|
0.71–1.29
|
0.777
|
1.44
|
0.88–2.37
|
0.147
|
Persistent oligoarthritis
|
0.80
|
0.69–0.92
|
0.003
|
1.36
|
1.07–1.73
|
0.013
|
Extended oligoarthritis
|
1.07
|
0.88–1.31
|
0.487
|
1.29
|
0.95–1.76
|
0.097
|
Psoriatic arthritis
|
1.16
|
0.90–1.50
|
0.248
|
1.11
|
0.74–1.65
|
0.618
|
Enthesitis-related arthritis
|
0.85
|
0.71–1.02
|
0.075
|
0.71
|
0.52–0.96
|
0.028
|
cJADAS-10
|
1.15
|
1.13–1.17
|
< 0.001
|
1.08
|
1.03–1.13
|
0.001
|
PGA score
|
1.33
|
1.29–1.38
|
< 0.001
| | | |
Inactive disease*
|
0.28
|
0.24–0.33
|
< 0.001
| | | |
No. of joints with active arthritis
|
1.10
|
1.08–1.12
|
< 0.001
| | | |
ESR
|
1.02
|
1.02–1.03
|
< 0.001
| | | |
C-HAQ total score
|
1.13
|
1.11–1.15
|
< 0.001
|
1.85
|
1.39–2.45
|
< 0.001
|
No functional limitations†
|
0.24
|
0.21–0.28
|
< 0.001
| | | |
Overall well-beingφ
|
1.30
|
1.27–1.34
|
< 0.001
| | | |
Pain intensityφ
|
1.25
|
1.22–1.28
|
< 0.001
|
1.04
|
0.97–1.11
|
0.265
|
Fatigueφ
|
1.17
|
.14–1.20
|
< 0.001
|
0.97
|
0.92–1.02
|
0.235
|
Copingφ
|
1.28
|
1.24–1.32
|
0.001
|
1.05
|
0.98–1.13
|
0.191
|
Treatment in past 12 months
|
Any systemic GCs
| | | |
1.35
|
0.91–2.01
|
0.137
|
Low-dose GCs (< 0.2 mg/kg)
|
2.06
|
1.43–2.96
|
< 0.001
| | | |
Any high-dose GCs (> 0.2 mg/kg)≠
|
1.90
|
1.36–2.67
|
< 0.001
| | | |
Intra-articular GCs
|
1.97
|
1.55–2.51
|
< 0.001
|
1.52
|
1.08–2.15
|
0.017
|
Any DMARD
|
1.67
|
1.42–1.97
|
< 0.001
|
1.70
|
1.33–2.19
|
< 0.001
|
Parent with academic degree
|
1.31
|
1.02–1.67
|
0.035
| | | |
Regular exercise in leisure time (patients aged ≥13)‡
|
0.46
|
0.38–0.57
|
< 0.001
| | | |
Physiotherapy
|
1.88
|
1.62–2.18
|
< 0.001
|
1.27
|
1.01–1.60
|
0.040
|
Occupational therapy
|
1.54
|
1.24–1.92
|
< 0.001
|
0.96
|
0.66–1.39
|
0.819
|
No physical therapy
|
0.55
|
0.47–0.64
|
< 0.001
| | | |