Variable | Univariate | Multivariable | ||||
---|---|---|---|---|---|---|
OR | 95% CI | P | OR | 95% CI | P | |
Age | 1.11 | 1.09–1.14 | < 0.001 | 1.09 | 1.04–1.14 | < 0.001 |
BMI | 1.07 | 1.05–1.10 | < 0.001 | 1.01 | 0.97–1.05 | 0.656 |
Female sex | 1.30 | 1.11–1.52 | 0.001 | 1.00 | 0.78–1.28 | 1.000 |
Disease duration | 0.99 | 0.99–1.00 | 0.049 | |||
Age at disease onset | 1.08 | 1.06–1.10 | < 0.001 | 1.03 | 1.00–1.06 | 0.041 |
RF-positive polyarthritis | 1.60 | 1.13–2.26 | 0.008 | 1.25 | 0.74–2.13 | 0.407 |
RF-negative polyarthritis | 0.98 | 0.83–1.16 | 0.831 | 0.73 | 0.55–0.97 | 0.028 |
Systemic JIA | 0.96 | 0.71–1.29 | 0.777 | 1.44 | 0.88–2.37 | 0.147 |
Persistent oligoarthritis | 0.80 | 0.69–0.92 | 0.003 | 1.36 | 1.07–1.73 | 0.013 |
Extended oligoarthritis | 1.07 | 0.88–1.31 | 0.487 | 1.29 | 0.95–1.76 | 0.097 |
Psoriatic arthritis | 1.16 | 0.90–1.50 | 0.248 | 1.11 | 0.74–1.65 | 0.618 |
Enthesitis-related arthritis | 0.85 | 0.71–1.02 | 0.075 | 0.71 | 0.52–0.96 | 0.028 |
cJADAS-10 | 1.15 | 1.13–1.17 | < 0.001 | 1.08 | 1.03–1.13 | 0.001 |
PGA score | 1.33 | 1.29–1.38 | < 0.001 | |||
Inactive disease* | 0.28 | 0.24–0.33 | < 0.001 | |||
No. of joints with active arthritis | 1.10 | 1.08–1.12 | < 0.001 | |||
ESR | 1.02 | 1.02–1.03 | < 0.001 | |||
C-HAQ total score | 1.13 | 1.11–1.15 | < 0.001 | 1.85 | 1.39–2.45 | < 0.001 |
No functional limitations† | 0.24 | 0.21–0.28 | < 0.001 | |||
Overall well-beingφ | 1.30 | 1.27–1.34 | < 0.001 | |||
Pain intensityφ | 1.25 | 1.22–1.28 | < 0.001 | 1.04 | 0.97–1.11 | 0.265 |
Fatigueφ | 1.17 | .14–1.20 | < 0.001 | 0.97 | 0.92–1.02 | 0.235 |
Copingφ | 1.28 | 1.24–1.32 | 0.001 | 1.05 | 0.98–1.13 | 0.191 |
Treatment in past 12 months | ||||||
Any systemic GCs | 1.35 | 0.91–2.01 | 0.137 | |||
Low-dose GCs (< 0.2 mg/kg) | 2.06 | 1.43–2.96 | < 0.001 | |||
Any high-dose GCs (> 0.2 mg/kg)≠ | 1.90 | 1.36–2.67 | < 0.001 | |||
Intra-articular GCs | 1.97 | 1.55–2.51 | < 0.001 | 1.52 | 1.08–2.15 | 0.017 |
Any DMARD | 1.67 | 1.42–1.97 | < 0.001 | 1.70 | 1.33–2.19 | < 0.001 |
Parent with academic degree | 1.31 | 1.02–1.67 | 0.035 | |||
Regular exercise in leisure time (patients aged ≥13)‡ | 0.46 | 0.38–0.57 | < 0.001 | |||
Physiotherapy | 1.88 | 1.62–2.18 | < 0.001 | 1.27 | 1.01–1.60 | 0.040 |
Occupational therapy | 1.54 | 1.24–1.92 | < 0.001 | 0.96 | 0.66–1.39 | 0.819 |
No physical therapy | 0.55 | 0.47–0.64 | < 0.001 |