Table 4 Previously published cases treated with RTX for severe refractory HSP

Donnithorne et el. [15]

3 children ages 17 (male), 14 (male), 10 (female) years old with severe chronic refractory HSP

Pillebout et al. [38]

22-year-old male with severe recurrent skin manifestations and nephritis in biopsy (RTX as only immunomodulation)

Kostik et al. [39]

7-year-old female with severe relapsing HSP with initial response followed by failure 2.5 years later

Tosounindou et al. [40]

61-year-old female with intractable GI manifestations that required repeated courses of RTX to maintain remission

El-Husseini et al. [41]

27-year-old male with drug-induced HSPN

Ishiguro et al. [42]

68-year-old female with refractory purpura nephritis

Pindi Sala [43]

49-year-old female with CS dependent HSP

Bellan et al. [16]

57-year-old female with recurrent purpura and proteinuria refractory to CTX and CS