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Table 3 Induction corticosteroid exposure through week 24 by CTP*

From: Pilot study comparing the childhood arthritis and rheumatology research alliance consensus treatment plans for induction therapy of juvenile proliferative lupus nephritis

Steroid Primarily IV
N = 15
Mixed Oral/IV
N = 17
Primarily Oral
N = 9
Oral prednisone or prednisolone
 n patients with complete med loga 14 14 9
 Total gm 5.8 (4–8.4) 8.4 (6.2–9.2) 16.1 (7.7–17.7)
 Total mg/kg 119 (72–142) 144 (94–160) 285 (114, 313)
 Difference from expected, mgb − 108 (− 685, + 65) + 367 (− 692, + 1440) − 338 (− 2650, + 1620)
IV methylprednisolone pulses
 n patient with complete med logsa 9 9 5
 Total number of pulse doses 12 (6–14) 5 (3–8) 1 (0, 3)
 Difference from expected, number of pulsesb − 1 (− 7, 0) −5 (− 5, 0) 0 (0, 0)c
  1. *All values presented as median (interquartile range), Abbreviations: CTP = Consensus treatment plan, IV = intravenous
  2. aPatients with incomplete steroid records were excluded from analysis
  3. bDifference from expected per CTP. A positive value (+) indicates more steroid was given than recommended per the CTP. A negative value (−) indicates less steroid was given per the CTP
  4. cIV pulses optional in the primarily oral CTP