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Table 2 Extractable nuclear antigen (ENA) antibody typing for siblings II-1 and II-2 at initial presentation, at relapse of disease and 8 months after ofatumumab

From: Successful use of ofatumumab in two cases of early-onset juvenile SLE with thrombocytopenia caused by a mutation in protein kinase C δ

ENA antibody typing

Patient II-1

Patient II-2

At presentation

At relapse

8 months after ofatumumab

At presentation

At relapse

8 months after ofatumumab

anti-NRNP

negative

negative

positive

negative

negative

equivocal

anti-SME

negative

negative

positive

negative

negative

positive

anti-Ro

negative

negative

positive

negative

negative

negative

anti-La

negative

negative

negative

negative

negative

negative

anti-Jo-1

negative

negative

negative

negative

negative

negative

anti-Scl70

negative

negative

negative

negative

negative

negative

other ENA antibodies

weakly positive

negative

negative

weakly positive

negative

negative