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Table 1 (abstract P271). See text for description.

From: Proceedings of the 25th European Paediatric Rheumatology Congress (PReS 2018)

Condition

Time

Assay

Number of replicates

p-value for detected significant changes

Control JSLE

0 h

mRNA

n=13

p=0.003 TLR2; p=0.01 S100A9 for Ctrl vs. JSLE

Stratified JSLE: CD16b p=0.01 IFN high vs Ctrl;

p=0.02 IFN high vs IFN low

protein

n=7 control

p=0.02 TLR; p=0.03 S100A9

n=6 JSLE

phagocytosis

n=7 control

p=0.04 E.coli

n=6 JSLE

IFNa

2 h

mRNA

n=6

p=0.03 CD16b

7 h

protein

n=5

p=0.02 CD16b

TNFa

30min

mRNA

n=5

n=6 required for analysis

2 h

protein

n=6

p=0.03 TLR2

Apoptotic supernatant

2h, 6h

mRNA

n=5

p=0.01 CD16b

6h

protein

n=5

p=0.02 CD16b