Table 1 Literature Review: Summary of the Case Reports of Neonatal Kawasaki Disease (0–28 days of age)
From: Kawasaki Disease in the neonate: case report and literature review
Pt | Ref | Age at onsetb (days) | Sex | Fever duration (days) | Rash | Oral changes | Extremity changesd | Red eyes | Cervical adenitis | CAA c | Other | CRP (high/ WNL) | IVIG res-ponse | CA outcome (last F/U) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 4 | 20 | F | 10 | + | + | + | + | – | + | DIC | high | + | WNL (8mos) |
2 | 6 | 10 | M | 5 | + | + | + | + | – | + | Apnea, seizures | WNL | + | CAA (2.5 yrs) |
3 | 7 | 8 | F | 9 | + | + | + | + | – | + | MR/AR | high | + | WNL (6 wks) |
4 | 8 | 16 | F | 13 | + | + | + | + | – | + | MR/TR | high | + | N/A |
5 | 9 | 20 | F | N/A | + | + | + | – | – | + | MR/AR | high | + | CAA (8 wks) |
6 | 10 | 8 | M | > 9 | + | – | + | – | – | + | Myocardial ischemiaa | high | + | CAA (9 wks) |
7 | 5 | 22 | F | 4 | + | – | + | – | – | – | – | high | + | WNL (3 mos) |
8 | 11 | 18 | M | 6 | + | + | + | – | – | – | Pneumonitis | WNL | + | WNL (6 wks) |
9 | 11 | 16 | M | 7 | + | + | + | – | – | – | Cough, diarrhea | high | + | WNL (11 yrs) |
10 | 12 | 21 | F | 4 | + | + | + | – | – | – | Abdominal pain vomiting | WNL | + | WNL (6 wks) |
11 | 12 | 14 | F | 3 | + | + | + | – | – | – | Hyperemia | WNL | + | WNL (6 mos) |
12 | 12 | 16 | M | 4 | + | + | + | – | – | – | Hyperemia | WNL | + | WNL |
13 | 13 | 5 | M | 1 | – | – | – | – | – | + | CHF, MR/AR | high | + | WNL(12mos) |
14 | 14 | 1 | M | 0 | – | – | – | – | – | + | DIC, pericardial effusion | N/A | N/A | WNL(12mos) |
15 | 15 | 1 | F | 0 | – | – | – | – | – | + | MI, CA vasculitis | N/A | N/A | death (day1) |
16 | PR | 15 | M | 5 | + | – | + | + | – | – | Apnea pneumonitis | WNL | + | WNL(12mos) |