Frequency of CD19+CD24hiCD38hi regulatory B cells is decreased in peripheral blood and synovial fluid of patients with juvenile idiopathic arthritis: a preliminary study

Table 3 Regulatory B cells percentages in different treatment subgroups

	No DMARD	DMARD	p value	No anti-TNF	Anti-TNF	p value
B cells (%)	14.96 ± 0.87 (n = 14)	16.19 ± 4.48 (n = 6)	0.7006	13.41 ± 1.07 (n = 8)	16.61 ± 2.20 (n = 12)	0.2757
CD24^hiCD38^hi Bregs (% in B cells)	17.11 ± 1.12 (n = 11)	13.38 ± 2.43 (n = 4)	0.1358	18.08 ± 1.42 (n = 6)	14.80 ± 1.45 (n = 9)	0.1469
B10 cells (% in B cells)	7.25 ± 1.14 (n = 14)	7.73 ± 2.30 (n = 5)	0.8408	6.16 ± 1.48 (n = 7)	8.09 ± 1.34 (n = 12)	0.3683

Bregs regulatory B cells, B10 cells IL-10 producing regulatory B cells, DMARD disease-modifying antirheumatic drug, JIA juvenile idiopathic arthritis, PB peripheral blood, SF synovial fluid, TNF tumor necrosis factor

ISSN: 1546-0096