| Total Cohort (n= 273) | Step up (n= 178) | Early Combination (n=66) | Biologic First (n=29) |
---|---|---|---|---|
Female N (%) | 196 (72) | 132 (74) | 44 (67) | 20 (69) |
White N (%) | 192 (70) | 130 (73) | 44 (67) | 18 (62) |
Age in yrs – mean (range) | 10 (1-18) | 10 (1-18) | 11 (1-17) | 11 (1-18) |
JIA Category N (%) | ||||
 Extended Oligoarticular | 6 (2) | 6 (3) | -- | -- |
 Polyarticular (RF-) | 174 (64) | 127 (71) | 35 (53) | 12 (41) |
 Polyarticular (RF+) | 48 (18) | 27 (15) | 17 (26) | 4 (14) |
 Psoriatic | 14 (5) | 6 (3) | 4 (6) | 4 (14) |
 Enthesitis-related | 24 (9) | 10 (6) | 8 (12) | 6 (21) |
 Undifferentiated | 6 (2) | 2 (1) | 2 (3) | 2 (7) |
Number of Active joints - mean (range) | 13 (5-50) | 12 (5-49) | 17 (5-50) | 11 (5-41) |
Physician Global Assessment of Disease Activity - mean (range) | 6 (0-10) | 5 (0-10) | 6 (1-10) | 6 (1-10) |
Juvenile Arthritis Disease Activity Score - mean (range) | 18 (5-29) | 17 (5-29) | 20 (6-29) | 20 (14-28) |
CHAQ Score - mean (range) | 1 (0-3) | 1 (0-3) | 1 (0-3) | 1 (0-3) |
Oral steroids prescribed at baseline - N (%) | 75 (27) | 50 (28) | 22 (33) | 3 (10) |