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Table 1 Anthropometric and biochemical parameters in pediatric childhood-onset SLE subjects and in healthy controls

From: Homocysteine, folate, hs-C-reactive protein, tumor necrosis factor alpha and inflammatory proteins: are these biomarkers related to nutritional status and cardiovascular risk in childhood-onset systemic lupus erythematosus?

Variables SLE Group
(n = 19)
Control Group
(n = 38)
p
BMI (kg/m2)a 24.6 (18.45–40.0) 20.83 (15.96–31.24) 0.001**
WC (cm)a 79.66 ± 8.94 72.25 ± 7.88 0.001**
Folate (ng/L)c 12.16 (5.8–19.25) 13.91 (10.4–26.2) 0.033*
Homocysteine (mmol/L)b 8.62 ± 2.36 7.29 ± 1.80 0.019*
Total Cholesterol (mg/dL)c 160.73 ± 42.76 152.75 ± 31.57 0.122
HDL (mg/dL)c 37.58 (27.0–61.0) 44.14 (25.0–99.0) 0.088
LDL (mg/dL)c 97.26 ± 26.16 89.75 ± 27.18 0.320
Triglycerides (mg/dL)c 152.42 (31.0–725.0) 88.16 (25.0–226.0) 0.003**
TNF - α (pg/mL)c 8.65 ± 2.55 7.04 ± 2.39 0.002**
hs-CRP (mg/L)c 4.41 (0.3–17.0) 0.84 (0.3–4.6) 0.000**
  1. *p < 0.05; post hoc Bonferroni **p < 0.005
  2. Values expressed as mean ± standard deviation. The difference between means was calculated by ANCOVA adjusted by: agea; age, BMI and cyanocobalamin intakeb; age and BMIc
  3. BMI = Body Mass Index, WC Waist Circumference, HDL High Density Lipoprotein, LDL = Low Density Lipoprotein, TNF – α Tumor Necrosis Factor – α, Hs-CRP high sensitive C- reactive protein