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Table 2 Demographic and clinical data from the initial evaluation of the patients who flared and did not during the study

From: Patients with juvenile idiopathic arthritis in clinical remission with positive power Doppler signal in joint ultrasonography have an increased rate of clinical flare: a prospective study

Total patients (n = 35) Flare (n = 20) No flare (n = 15) p
Mean age ± SD (years) 11.5 ± 3.6 11.6 ± 4 0.856‡
Mean age at JIA onset ± SD (years) 3.8 ± 2.8 5.1 ± 3.5 0.298‡
Mean time of JIA duration ± SD (years) 7.6 ± 3.1 6.3 ± 4.1 0.202‡
Females 17 11 0.430a
Joint involvement    0.486†
Oligoarticular (Oligoarticular persistent) 7 7  
Polyarticular (Oligoarticular extended + polyarticular) 13 (8 + 5) 8 (4 + 4)  
ANA 12 8 0.693†
Previous uveitis 4 0 0.119a
Type of clinical remission    0.129a
On medication 17 9  
Mean time on clinical remission ± SD 1.2 ± 0.5 years 2.6 ± 3.2 years 0.064‡
CHAQ median (min – max) 0 (0–0.375) 0 (0–0.375) 0.805‡
Global physician’s VAS median (min – max) 0 (0–1)b 0 (0) 0.805‡
Global parents or patient’s VAS median (min – max) 0 (0–4) 0 (0–5) 0.352‡
ESR mm3/h mean ± SD 7.5 ± 5.7 6 ± 3.5 0.587‡
CRP mg/dL mean ± SD 0.25 ± 0.15 0.23 ± 0.14 0.730‡
  1. SD standard deviation, JIA juvenile idiopathic arthritis, ANA antinuclear antibody, ESR erythrocyte sedimentation rate, CRP C-reactive protein, CHAQ Childhood Health Assessment Questionnaire, VAS visual analogue scale
  2. aFisher’s test, † chi-squared test, ‡ Mann-Whitney test
  3. bOne patient received a Global physician’s VAS of 1 due to joint limitation explained by previous joint damage and not due to active disease at the time of evaluation