Effects of age and gender on reference levels of biomarkers comprising the pediatric Renal Activity Index for Lupus Nephritis (p-RAIL)

Table 3 Biomarker vs. age group

Variable	Age = 3 - < 5 years			Age = 5 - < 10 years			Age = 10 - < 15 years			Age = 15 - < 18 years			p-value of F
Variable	N	Mean	SD	N	Mean	SD	N	Mean	SD	N	Mean	SD
KIM-1 (pg/ml)	92	5.68	1.01	90	5.78	0.97	92	5.94	0.91	92	6.15	0.97	0.008
NGAL (ng/ml)	93	1.42	1.47	90	1.63	1.30	92	2.08	1.17	92	2.59	1.08	0.0001
MCP-1 (pg/ml)	88	5.00	0.92	89	5.11	0.97	92	5.27	0.98	91	5.45	1.00	0.012
HPX (ng/ml)	92	6.23	0.75	90	6.40	0.65	92	6.56	0.85	92	6.48	1.22	0.082
CP (ng/ml)	92	5.77	0.76	90	6.17	0.47	92	6.20	0.61	92	6.14	0.59	0.0001
ADP (ng/ml)	77	1.95	0.98	71	2.10	0.94	82	1.96	0.98	65	1.50	1.58	0.014
Creatinine (mg/dl)	93	4.19	0.77	90	4.48	0.64	92	4.86	0.59	92	5.07	0.66	0.0001
MALB (mg/l)	92	2.20	0.73	90	2.32	0.72	92	2.72	1.09	92	2.73	1.28	0.0001

ISSN: 1546-0096