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Table 16 (Abstract P238). See text for description

From: Proceedings of the 24th Paediatric Rheumatology European Society Congress: Part two

 

PharMetrics

MarketScan

Baseline characteristics*

Abatacept-treated patients

n = 225

Other bDMARD-treated patients

n = 1346

Abatacept-treated patients

n = 238

Other bDMARD-treated patients

n = 1252

Female

183 (81.3)

948 (70.4)

195 (81.9)

927 (74.0)

Age, mean (SD)

13.17 (3.2)

10.86 (3.5)

12.36 (3.2)

11.03 (3.5)

Baseline co-morbidities

    

Asthma

18 (8.0)

63 (4.7)

21 (8.8)

46 (3.7)

Cardiovascular disease

22 (9.8)

53 (3.9)

18 (7.6)

49 (3.9)

Hospitalized infections

    

Uveitis

14 (6.2)

28 (2.1)

10 (4.2)

27 (2.2)

Biologic DMARDs

22 (9.8)

140 (10.4)

22 (9.2)

159 (12.7)

Non-biologic DMARDs

109 (48.4)

2 (0.1)

84 (35.3)

2 (0.2)

Inpatient visits, mean (SD)

139 (61.8)

614 (45.6)

105 (44.1)

476 (38.0)

Outpatient visits, mean (SD)

0.21 (0.8)

0.07 (0.4)

0.18 (0.8)

0.07 (0.3)

 

12.01 (10.2)

7.89 (9.0)

11.63 (10.7)

7.43 (8.9)

Outcomes

HIs, IR (95% CI)

Uveitis, IR (95% CI)

1.4 (0.3, 4.1)

1.6 (0.5, 3.8)

1.7 (1.1, 2.5)

3.1 (2.4, 3.9)

2.4 (0.9, 5.3) 3.6 (1.7, 6.9)

1.6 (1.0, 2.4)

3.3 (2.5, 4.2)

  1. Data are n (%) unless indicated otherwise
  2. *During the 6-month period prior to treatment. HI = hospitalized infection; IR = incidence rate