Skip to main content

Table 1 Clinical and MRI examination data in patients with cervical spine involvement

From: Clinical and MRI outcome of cervical spine lesions in children with juvenile idiopathic arthritis treated with anti-TNFα drugs early in disease course

 

G

JIA

iMRI age (y)

Biologics

Treatment duration with biologics(y)

last MRI results

Clinical outcome

Inflam

Chronic changes

1

M

pJIA

ANA+

4.1

ETA

ADA

0.7

1.3

no

no

no inflam.

2

F

pJIA

7.6

IFX

1.8

no

no

no inflam.

3

F

pJIA

ANA+

6.9

ETA

1

no

no

no inflam.

4

F

oJIA

3.2

ETA

2.8

no

no

no inflam.

5

M

pJIA

ANA+

HLAB27+

2.4

IFX

0.5

peristent

no

Inflam. in 2 perif.joints

6

M

pJIA

14.8

IFX

0.5

persistent

no

LROM

Inflam. in 5 perifer.joints

7

F

jPsA

3.6

IFX

2.1

no

no

no treatment for 2.3y

8.2

IFX

1.5

no

no

LROM

no inflam.

8

F

pJIA

ANA+

8.7

IFX

3.5

peristent

yes

LROM

Inflam. in 2 perif.joint

9

F

oJIA

ANA+

15.1

IFX

1.2

no

no

no inflam.

10

F

pJIA

2.7

ADA

TOC

ETA

0.3

1.3

1.7

no

no

LROM

no inflam.

11

F

oJIA

14.6

ADATOC

0.4

0.8

no

no

Inflam. in 1perif.joint

12

F

poJIA

ANA+

RF+

3.1

IT

IFX

0.5

4.5

no

yes

no inflam.

uveitis

noanti-TNFα for 2y

MTX

13

F

poJIA

ANA+

4.8

IT

IFX

0.6

3.6

no

no

no inflam.

no treatment for 2.2y

14

F

pJIA

2.5

IT

ETA

ADA

0.3

0.5

0.4

2.4

no

no

no inflam.

15

M

pJIA

ANA+

4.2

IT

MTX only

1.5

2.5

no

yes

no treatment for 1.4y

  1. G gender, F female, M male, pJIA polyarticular juvenile idiopatic arthritis, oJIA extended oligoarthritis JIA, poJIA persistent oligoarthritis JIA, jPsA juvenile psoriatic arthritis, iMRI age of child when initial magnetic resonance imaging of cervical spine confirmed cervical spine arthritisBiologics, IFX infliximab, ETA etanercept, ADA adalimumab, and Anti IL-6, TOC tocilizumab, IT initial treatment with corticosteroids and methotrexate (MTX) received all children, duration of IT was written only in children with delay introduction of biologics Last MR: Inflam – no inflammation, persistent inflammation of cervical spine seen on last MRI, chronic changes - no chronic changes, yes- chronic changes seen on last MRI Clinical outcome: no inflammation – no inflammation in other peripheral joints, X periph.joints- number of peripheral joints presented with inflammation