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Table 3 Infant and maternal characteristics among singleton Juvenile Idiopathic Arthritis (JIA) case categories and controls born in WA State, 1997–2010

From: Juvenile idiopathic arthritis in relation to perinatal and maternal characteristics: a case control study

 

Persistent Oligoarthritis

Extended Oligoarthritis

RF+ Polyarthritis

RF- Polyarthritis

Systemic JIA

Enthesitis Related Arthritis

Psoriatic Arthritis

Undifferentiated JIA

N a (%)

389

31.50%

73

5.90%

60

4.90%

256

20.70%

71

5.80%

262

21.20%

62

5.00%

39

3.20%

 

ORb

95% CI

ORb

95% CI

ORb

95% CI

ORb

95% CI

ORb

95% CI

ORb

95% CI

ORb

95% CI

ORb

95% CI

Infant factors

 Gest. age (wks)

   < 37

0.71

0.43, 1.18

-

-

2.23

1.04, 4.80

0.64

0.33,1.21

1.67

0.76, 3.69

1.9

1.27, 2.86

-

-

-

-

  37–42

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

  42+

0.88

0.60, 1.29

1.31

0.62, 2.75

0.74

0.29, 1.89

0.83

0.52, 1.33

1.07

0.48, 2.35

0.81

0.51, 1.29

0.79

0.31, 2.00

-

-

 Size for gest age

  SGA

0.95

0.64, 1.40

0.79

0.31, 1.99

-

-

0.97

0.60, 1.55

1.03

0.44, 2.41

1.03

0.65, 1.62

1.31

0.55, 3.13

2.64

1.18, 5.94

  AGA

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

  LGA

1.16

0.82, 1.63

0.99

0.45, 2.18

1.42

0.60, 3.40

1.07

0.69, 1.65

0.8

0.32, 2.01

0.93

0.59, 1.47

-

-

-

-

 Birth weight (g)

   < 2500

0.84

0.51, 1.40

0.24

0.03, 1.77

2.29

1.03, 5.13

1.1

0.63, 1.92

1.88

0.85, 4.15

1.18

0.69, 2.02

-

-

-

-

  2500–3999

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

   ≥ 4000

0.85

0.62, 1.17

0.55

0.24, 1.28

0.66

0.26, 1.67

0.89

0.61, 1.31

-

-

0.96

0.67, 1.38

0.79

0.35, 1.74

-

-

Maternal Factors

 Cesarean Section

  Yes

1.17

0.92,1.66

0.93

0.52, 1.66

1.8

1.00, 3.20

1.07

0.78, 1.46

0.9

0.49, 1.65

1.14

0.84, 1.55

1.15

0.62, 2.13

0.84

0.35, 2.01

  No

1

Reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

 No. prior birthc,e

  0

1

Reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

  1

0.88

0.69, 1.12

1.02

0.60, 1.74

0.72

0.38, 1.37

0.78

0.58, 1.06

0.92

0.53, 1.59

1.36

1.02, 1.82

1.15

0.65, 2.04

0.66

0.31, 1.41

  2

0.71

0.52, 0.98

0.53

0.27, 1.04

0.67

0.27,1.67

0.63

0.42, 0.95

0.94

0.47, 1.86

0.83

0.56, 1.24

0.53

0.21, 1.33

0.6

0.25, 1.44

  3

0.55

0.32, 0.94

-

-

1.77

0.75, 4.14

0.89

0.51, 1.53

0.64

0.24, 1.70

0.96

0.54, 1.69

0.71

0.26, 1.94

-

-

  4+

0.32

0.15, 0.71

-

-

-

-

1.24

0.70, 2.18

-

-

0.65

0.31, 1.39

-

-

-

-

 Any fetal loss

  None

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

  1+

1.06

0.76, 1.47

0.77

0.35, 1.70

2

1.00, 4.00

2.2

1.55, 3.12

1.9

1.00, 3.64

1.59

1.16, 2.17

2.85

1.57, 5.17

1.42

0.61, 3.30

 No. prior fetal losses (<20 w)c

  None

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

  1+

1.11

0.80, 1.54

0.84

0.38, 1.88

1.71

0.83, 3.51

2.08

1.46, 2.97

1.68

0.86, 3.28

1.56

1.13, 2.14

2.62

1.44, 4.78

1.57

0.68, 3.65

 No. prior fetal losses ((≥20 w)c, d

  None

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

1

reference

  1+

-

-

-

-

-

-

2.25

0.96, 5.25

-

-

1.9

0.86, 4.20

-

-

-

-

  1. aEstimates do not include polyarthritis with unknown RF status
  2. bAll estimates are adjusted for maternal age and birth year
  3. cEstimates are restricted to 839 case mothers and 4,015 control mothers with prior pregnancy
  4. dIn addition to maternal age and birth year, also adjusted for paternal age
  5. eP for trends: persistent oligo: ****P0.0001; extended oligo, ***P0.0075. All others are > 0.05
  6. Estimates in italics are statistically significant
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Pediatric Rheumatology

ISSN: 1546-0096