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Table 2 The sensitivity, specificity, positive and negative likelihood ratios for diagnosis of JSpA (clinical gold standard) predicted by MRI global assessment, by the ASAS definition of a positive MRI and for ‘adapted’ ASAS definitions, including BME lesions only seen on one slice or location, synovitis, capsulitis, retro-articular enthesitis, structural lesions and combinations of these features

From: ASAS definition for sacroiliitis on MRI in SpA: applicable to children?

  N Sensitivity Specificity LR LR
% (95% CI) % (95% CI) + -
Global assessment 30 49 (34.1–63.9) 89 (78.1–95.3) 4.45 0.57
ASAS definition 14 26 (13.9–40.4) 97 (88.8–99.6) 8.67 0.76
ASAS OR focal lesions 20 36 (22.7–51.5) 95 (86.5–99.0) 7.20 0.67
ASAS OR synovitis 20 32 (19.1–47.1) 92 (82.2–97.3) 4 0.74
ASAS OR capsulitis 17 32 (19.1–47.1) 97 (88.8–99.6) 10.67 0.70
ASAS OR retroarticular enthesitis 18 30 (17.3–44.9) 94 (84.3–98.2) 5 0.74
ASAS OR structural 16 28 (15.6–42.6) 95 (86.5–99.0) 5.60 0.76
ASAS OR focal lesions OR synovitis 26 43 (28.3–57.8) 90 (80.1–96.4) 4.30 0.63
ASAS OR focal lesions OR capsulitis 23 43 (28.3–57.8) 95 (86.5–99.0) 8.60 0.60
ASAS OR focal lesions OR synovitis OR capsulitis 28 47 (32.1–61.9) 90 (80.1–96.4) 4.7 0.59
  1. (N Number of sacroiliitis-positive patients, 95% CI 95% confidence Interval, LR+ positive likelihood ratio, LR - negative likelihood ratio, ASAS Assessment of Spondyloarthritis International Society)