aSvdH | Mean CHR | |||||||
---|---|---|---|---|---|---|---|---|
Univariate analyses | Multivariate analyses | Univariate analyses | Multivariate analyses | |||||
Variables assessed within 15 years: | B (95% CI) | P value | B (95% CI) | P value | B (95% CI) | P value | B (95% CI) | P value |
Oligoarticular onseta | −48.1 (−85.3 to −10.9) | 0.012 | 0.047 (0.005 to 0.090) | 0.028 | ||||
Polyarticular courseb | NA | NA | −0.060 (−0.120 to 0.000) | 0.048 | ||||
HLA-DRB1*04 positive | 67.2 (28.8 to 105.5) | 0.001 | NA | NA | ||||
HLA-B27 positive | NA | NA | 0.057 (0.011 to 0.102) | 0.016 | 0.047 (0.013 to 0.082) | 0.009 | ||
No. joints with LROM at 15 yearsc | 5.9 (4.7 to 7.2) | <0.001 | 4.8 (3.4 to 6.3) | <0.001 | −0.005 (−0.007 to−0.004) | <0.001 | −0.004 (−0.006 to−0.002) | <0.001 |
ESR at 15 years, mm/h | 2.6 (1.7 to 3.5) | <0.001 | 1.1 (0.3 to 1.9) | 0.010 | −0.002 (−0.003 to−0.001) | <0.001 | ||
CRP at 15 years, mg/l | 2.3 (1.2 to 3.3) | <0.001 | NA | NA | ||||
HAQ at 15 years | 53.5 (22.2 to 84.7) | 0.001 | −0.065 (−0.100 to −0.031) | <0.001 | −0.042 (−0.071 to −0.012) | 0.007 | ||
Total time with active disease at 15-year follow-up, years | 5.1 (1.0 to 9.1) | 0.015 | −0.007 (−0.011 to −0.002) | 0.005 |