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Table 40 (abstract P107). Core set measures values at different time points in the 3 groups of patients (only key results are reported)

From: Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part one

 

OFF PDN

OFF PDN

PDN ON

P value

Failure: No

Failure: Yes

Failure Yes or No

Group 1

Group 2

Group 3

N = 57

N = 24

N = 58

Month 6: MD global

0.5 (0–2)

2.6 (0.8–5)

3 (0.6–6)

<0.0001

 Parent global

1 (0–1.8)

3.1 (0.5–5)

2.5 (0.8–5.8)

0.0002

 CHAQ

0.1 (0–0.5)

0.1 (0–0.9)

0.5 (0–1.9)

0.0007

 DAS

3 (0–5)

6.5 (1–11.5)

8 (4–12)

<0.0001

 CMAS

47 (42–51)

45 (35–48.5)

35 (21.5–47)

0.0001

 CHQ-PhS

51.8 (46.2–54.9)

47.5 (20.3–54.1)

36.3 (16.6–50.6)

<0.0001

 MMT

77 (70–80)

70 (59–78.5)

64 (51–75)

<0.0001

Month 12: MD global

0 (0–1)

2.6 (1–5.5)

3 (0.6–6)

<0.0001

Month 18 DAS

0 (0–3)

6 (2.5–11.5)

9 (2–12)

<0.0001

Month 24: CMAS

50 (48–52)

42 (36–50)

36.5 (21.5–48)

<0.0001