Table 37 (abstract P98). Characteristics of those patients with anti-synthetase autoantibodies
From: Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part one
Patient | 1 | 2 | 3 | 4 | 5 | 6 |
|---|---|---|---|---|---|---|
Diagnostic label | Overlap with scleroderma and arthritis | Overlap with scleroderma and arthritis | Overlap with arthritis | Initially diagnosed with PAN, then myositis and SLE | JDM | Overlap with systemic sclerosis |
Age at onset (years) | 9.06 | 9.41 | 15.47 | 13.06 | 12.53 | 14.43 |
Length of follow up (years) | 0.67 | 11.5 | 1.33 | 6.47 | 3.5 | 2.76 |
Specific antibody | Jo1 | Jo1 | Jo1 | PL12 | PL7 | PL12 |
Muscle | Severe myositis | Myositis | Myositis | Myositis | Myositis | Destructive necrotizing, myopathy on biopsy |
Skin | Gottron’s Heliotrope rash | Gottron’s Mechanics hands | Gottron’s Heliotrope rash | Heliotrope rash Erythematous rash on forearms | Gottron’s Heliotrope rash | Gottron’s Heliotrope rash Skin ulceration and calcinosis Mechanics hand |
Joint | Polyarthritis with contractures | Nil of note | Arthritis | Nil of note | Nil of note | Nil of note |
Lung | Normal | Normal | Normal | ILD | ILD | ILD |
Mortality to date | Alive | Alive | Alive | Alive | Alive | Alive |