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Table 4 Associations between cholesterol fractions and disease characteristics, fatness, and physical activity P values with correlation coefficients, and 95 % confidence interval in brackets

From: Lipoprotein cholesterol fractions are related to markers of inflammation in children and adolescents with juvenile idiopathic arthritis: a cross sectional study

Patients TC mmol/l HDLc mmol/l LDLc mmol/l
Gender T-test 0.05 0.19 0.12
Tanner stage (≤4 or = 5) T-test 0.87 0.51 0.85
Subgroup of JIA
ANOVA
0.05 0.85 0.09
Treatment a
ANOVA
0.83 0.68 0.98
Disease duration
Bivariate correlation
0.93 0.19 0.84
Primary endpoints:
MRP 8/14
Bivariate correlation, p value
Pearson correlation coefficient, r
95 % confidence interval
0.20 <0.0005*
−0.343
(−0.474 to −0.201)
0.92
CRP
Bivariate correlation, p value
Pearson correlation coefficient, r
95 % confidence interval
0.83 0.043
−0.167
(−0.319 to–0.015)
0.63
JADAS 27 b
Nonparametric correlation
0.66 0.72 0.92
Waist-to-height ratio
Bivariate correlation, p value
Pearson correlation coefficient r
95 % confidence interval
0.824 0.018
−0.187
(−0.345 to–0.033)
0.199
BMI SDS
Bivariate correlation
0.15 0.13 0.49
Counts per minute (cpm) (133 patients)
Bivariate correlation
0.23 0.25 0.33
Sedentary time (minutes/day) (133 patients)
Bivariate correlation
0.23 0.61 0.11
High activity (minutes/day) (133 patients)
Bivariate correlation
0.15 0.21 0.17
  1. TC total cholesterol, HDLc high density fraction of cholesterol, LDLc low density fraction of cholesterol
  2. *Significance (p) is given as two-tailed and α selected after Bonferoni correction as 0.004 (12 independent tests)
  3. aTreatment: Methotrexate versus TNF-α inhibitor versus IL-6 receptor inhibitor versus T-cell co-stimulation inhibitor CTLA-4-Ig
  4. bJADAS27 (0–57): a composite score of: number of joints with active disease (max 27), Physician global VAS, patient/parent global VAS and truncated ESR (tESR)
  5. All parametric bivariate correlations have been performed after log10 transformation