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Table 1 Oxidative stress parameters according to the subjects genotype groups

From: Distribution of MEFV gene mutations and R202Q polymorphism in the Serbian population and their influence on oxidative stress and clinical manifestations of inflammation

Oxidative stress parameters

MEFV mutation carriers (n = 11)

R202Q homozygotes (n = 10)

MEFV/R202Qhomo (n = 20)

Control (n = 80)

TBARS in plasma (μmol/L)

2.36 ± 0.15

2.21 ± 0.12

2.327 ± 0.125

2.33 ± 0.46

TBARS in erythrocytes (nmol/gHb)

124.79 ± 46.41

132.09 ± 94.96

130.80 ± 68.86*

82.46 ± 34.16

AOPP (μmol/L)

40.15 ± 29.63

27.55 ± 17.59

32.63 ± 14.57

22.49 ± 20.24

SOD in plasma (U/ml)

3.61 ± 0.77

4.12 ± 0.46**

3.71 ± 0.48*

2.92 ± 0.96

SOD in erythrocytes (U/gHb)

10.37 ± 7.44

9.017 ± 2.09

9.02 ± 7.44

12.95 ± 7.54

Catalase in erythrocytes (U/ml/mgHb)

62.66 ± 44.04

75.71 ± 15.66

65.86 ± 23.98

80.13 ± 36.76

  1. Values are shown as mean ± SD or median ± IQR
  2. MEFV/R202Qhomo MEFV mutation carrier plus R202Q homozygotes group, Control N/N and R202Q/N, TBARS thiobarbituric acid reactive substances, AOPP advanced oxidation protein products, SOD superoxide dismutase
  3. *p < 0.05; **p < 0.001
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Pediatric Rheumatology

ISSN: 1546-0096