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Table 1 Oxidative stress parameters according to the subjects genotype groups

From: Distribution of MEFV gene mutations and R202Q polymorphism in the Serbian population and their influence on oxidative stress and clinical manifestations of inflammation

Oxidative stress parameters MEFV mutation carriers (n = 11) R202Q homozygotes (n = 10) MEFV/R202Qhomo (n = 20) Control (n = 80)
TBARS in plasma (μmol/L) 2.36 ± 0.15 2.21 ± 0.12 2.327 ± 0.125 2.33 ± 0.46
TBARS in erythrocytes (nmol/gHb) 124.79 ± 46.41 132.09 ± 94.96 130.80 ± 68.86* 82.46 ± 34.16
AOPP (μmol/L) 40.15 ± 29.63 27.55 ± 17.59 32.63 ± 14.57 22.49 ± 20.24
SOD in plasma (U/ml) 3.61 ± 0.77 4.12 ± 0.46** 3.71 ± 0.48* 2.92 ± 0.96
SOD in erythrocytes (U/gHb) 10.37 ± 7.44 9.017 ± 2.09 9.02 ± 7.44 12.95 ± 7.54
Catalase in erythrocytes (U/ml/mgHb) 62.66 ± 44.04 75.71 ± 15.66 65.86 ± 23.98 80.13 ± 36.76
  1. Values are shown as mean ± SD or median ± IQR
  2. MEFV/R202Qhomo MEFV mutation carrier plus R202Q homozygotes group, Control N/N and R202Q/N, TBARS thiobarbituric acid reactive substances, AOPP advanced oxidation protein products, SOD superoxide dismutase
  3. *p < 0.05; **p < 0.001