|
Oxidative stress parameters
|
MEFV mutation carriers (n = 11)
|
R202Q homozygotes (n = 10)
|
MEFV/R202Qhomo (n = 20)
|
Control (n = 80)
|
|---|
|
TBARS in plasma (μmol/L)
|
2.36 ± 0.15
|
2.21 ± 0.12
|
2.327 ± 0.125
|
2.33 ± 0.46
|
|
TBARS in erythrocytes (nmol/gHb)
|
124.79 ± 46.41
|
132.09 ± 94.96
|
130.80 ± 68.86*
|
82.46 ± 34.16
|
|
AOPP (μmol/L)
|
40.15 ± 29.63
|
27.55 ± 17.59
|
32.63 ± 14.57
|
22.49 ± 20.24
|
|
SOD in plasma (U/ml)
|
3.61 ± 0.77
|
4.12 ± 0.46**
|
3.71 ± 0.48*
|
2.92 ± 0.96
|
|
SOD in erythrocytes (U/gHb)
|
10.37 ± 7.44
|
9.017 ± 2.09
|
9.02 ± 7.44
|
12.95 ± 7.54
|
|
Catalase in erythrocytes (U/ml/mgHb)
|
62.66 ± 44.04
|
75.71 ± 15.66
|
65.86 ± 23.98
|
80.13 ± 36.76
|
- Values are shown as mean ± SD or median ± IQR
-
MEFV/R202Qhomo MEFV mutation carrier plus R202Q homozygotes group, Control N/N and R202Q/N, TBARS thiobarbituric acid reactive substances, AOPP advanced oxidation protein products, SOD superoxide dismutase
- *p < 0.05; **p < 0.001
