Table 2 Comparison of cases with JIA, cSLE and JDM with autoimmune disorders among first-degree relatives

Any autoimmune disease

1,488 (31.8)

204 (31.9)

90 (20.5)^{a b}

<0.001

Inflammatory Arthritis -(AS, Spondyloarthropathy, JIA, RA)

608 (13.0)

59 (9.2)^a

19 (4.3)^{a b}

<0.001

 Ankylosing spondylitis

61 (1.3)

1 (0.2)^a

2 (0.5)

0.014

 Spondyloarthropathy

36 (0.8)

0 (0.0)

0 (0.0)

0.015

 JIA

241 (5.2)

14 (2.2)^a

4 (0.9)^a

<0.001

 RA

340 (7.3)

50 (7.8)

15 (3.4)^{a b}

0.007

Crohn’s disease or ulcerative colitis

126 (2.7)

4 (0.6)^a

5 (1.1)

0.002

Acute anterior uveitis

15 (0.3)

0 (0.0)

0 (0.0)

0.169

Psoriasis

372 (8.0)

16 (2.5)^a

22 (5.0)

<0.001

SLE

77 (1.7)

71 (11.1)^a

5 (1.1)^b

<0.001

Multiple Sclerosis

45 (1.0)

7 (1.1)

5 (1.1)

0.905

Autoimmune thyroiditis

248 (5.3)

17 (2.7)^a

24 (5.5)

0.015

Celiac

36 (0.8)

5 (0.8)

6 (1.4)

0.439

Type 1 Diabetes

147 (3.1)

47 (7.4)^a

13 (3.0)^b

<0.001

Other autoimmune

214 (4.6)

32 (5.0)

20 (4.6)

0.893