Recurrent oral aphtosis (mandatory, seen by a physician and recurrence at least 3 times in a year) | |
plus at least two of | |
Genital ulceration (or aphthosis, at least once) | |
Skin lesions (erythema nodosum, necrotic folliculitis and papulopustular lesions, (post adolescent, not receiving steroids) | |
Ocular lesions (posterior uveitis, total uveitis, retinal vasculitis) | |
Positive pathergy test (done by needle prick (oblique insertion of 20- gauge needle) or intradermal saline injection and read at 48h by a physician. Positive reactions include: papula, pustula or papula with surrounding erythema) |