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Table 6 Factors associated with biologic agent use in idiopathic uveitis

From: Medication use in juvenile uveitis patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance Registry

     Multivariable Logistic Regression
Variable Biologics No Biologics Univariate P value Odds Ratio 95 % CI P value
N = 49 N = 43
Age at onset, yrs    0.35    0.90
 Median (IQR) 7.7 (5.1-10.2) 8.9 (6.8-11.4)     
Gender    0.21    0.07
 Female 24 (49 %) 27 (63 %)     
 Male 25 (51 %) 16 (37 %)     
Ethnicity    0.54    0.92
 Hispanic 5 (10 %) 7 (16 %)     
 Non-Hispanic 44 (90 %) 36 (84 %)
Race    0.20    0.87
 Caucasian 35 (73 %) 36 (86 %)     
 Non-Caucasian 13 (27 %) 6 (14 %)
Uveitis type    0.44    0.82
 Anterior 27 (55 %) 30 (70 %)     
 Pan 13 (27 %) 6 (14 %)
 Intermediate 7 (14 %) 5 (12 %)
 Posterior 2 (4 %) 2 (5 %)
ANA status    0.07***    
 Positive 20 (49 %) 10 (29 %)   3.0 1.0-8.6 0.04*
 Negative 21 (51 %) 25 (71 %)   Reference   
Any complication 39 (81 %) 32 (74 %) 0.46    0.16
 Cataracts 26 (53 %) 9 (21 %) 0.002* 5.6 1.8-17.2 0.001*
  1. IQR interquartile range, CI confidence interval
  2. *Statistically significant, ***Trend